This blog is meant to allow Fragment-based Drug Design Practitioners to get together and discuss NON-CONFIDENTIAL issues regarding fragments.
22 April 2013
Poll Results - Number of Fragments in the Screen
The poll is closed! So, the question was
I think it is fair to say that the average number of fragments per fragment mixture for NMR pooling is 6. I typically say five is the goal and if you can squeeze in more good on ya! I don't think the limitation is chemical shifts, I think it is solubility. I would love to hear what others think is the limitation.