A friend recently asked if I knew of any commercial fragment collections. She knows someone in academia who is interested in exploring fragment-based ligand discovery, and would like to get started with a well-curated library.
At Sunesis, we used custom-built, disulfide-containing fragments for Tethering, but of course most techniques aren't limited to disulfides.
So everyone, does your company sell fragments? Now is your chance to get some free advertising!
Or have you purchased fragment libraries? Did you like them? If not, now is your chance to get some free complaining!