Practical Fragments

In the olden days (1980s), during the cold war, Russia was "a riddle wrapped in a mystery inside an enigma".  Kremlin Watching w...

So, not everybody agrees with me on what a fragment is .  As has been pointed out years ago, FBDD can be a FADD .  In this paper , from ea...

Bugs are bad.  I hate bugs.  Bugs of all kinds.  In our part of the world we have a particularly noxious, invasive bug called the stink bug...

As illustrated earlier this year , kinases have been a fertile field for fragments. In a recent issue of J. Med. Chem. , Jason Kettle and co...

The sequencing of the human genome has thrown up lots of potential targets, but choosing which ones to pursue is difficult: many are not bio...