Practical Fragments

This blog is meant to allow Fragment-based Drug Design Practitioners to get together and discuss NON-CONFIDENTIAL issues regarding fragments.

Showing posts with label dynamics. Show all posts
Showing posts with label dynamics. Show all posts
23 February 2026

Twelfth Novalix Biophysics in Drug Discovery Conference

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Last week the Twelfth Novalix Biophysics in Drug Discovery Conference was held for the first time in La Jolla, California. It’s been severa...
02 December 2024

Mapping protein conformations with fragments

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Proteins can be remarkably dynamic, and, as we noted recently, different conformational states can reveal different pockets for small molec...
15 July 2024

SAR by TR-HT-SAXS

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Well that’s an acronym soup! SAR by NMR was the first practical fragment-finding method, and over the years Practical Fragments has covere...
18 June 2018

Fifth NovAliX Biophysics in Drug Discovery Conference

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Last week NovAliX  held its biophysics meeting  outside of Strasbourg for the first time. Naturally they chose Boston, one of the most Euro...
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