Practical Fragments

This blog is meant to allow Fragment-based Drug Design Practitioners to get together and discuss NON-CONFIDENTIAL issues regarding fragments.

Showing posts with label detergent. Show all posts

Showing posts with label detergent. Show all posts

17 January 2022

An epidemic of aggregators, and suggestions for cures

COVID-19 has been with us for over two years now. While the human effects have been unquestionably negative, for science it has been the bes...

29 August 2009

Avoiding will-o’-the-wisps: aggregation artifacts in activity assays

The phenomenon of aggregation is the drug hunter’s quicksand. A prerequisite for using biochemical assays to study fragments – or any low-af...

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