Showing posts with label TINS. Show all posts
Showing posts with label TINS. Show all posts
11 July 2016

Fragments deliver a chemical probe for CBP and EP300

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As we mentioned last week, July is bromodomain month at Practical Fragments . Today we’ll start by looking at two closely related bromodo...
30 July 2014

Fragments in the Caribbean

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Last week saw the inaugural Zing FBDD conference in Punta Cana, Dominican Republic. Zing has been around only since 2007, and seems to focu...
2 comments:
16 July 2014

You Probably Already Knew This...

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Academics can spend time and resources doing, and publishing, things that people in the industry already "know".  This keeps the ...
4 comments:
09 December 2013

Docking vs TINS on a GPCR

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Practical Fragments has featured a number of posts comparing various fragment-finding methods. In some cases there is good agreement , whil...
2 comments:
15 May 2013

30% of all Posts...

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NOTE: Blogger blew up my post when I published it.  I have fixed what I can.  Blogger keeps on blowing up this post after I edit it.   I ha...
3 comments:
02 October 2010

TINS and STD and SPR – oh my!

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Following up on our last post on the use of the NMR technique TINS applied to a membrane protein, the same research group has now compared ...
28 September 2010

Fragments vs membrane proteins with TINS

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Fragment-based ligand discovery owes much of its success to the rise of biophysical techniques such as NMR, crystallography, and – more rece...
31 December 2009

Current Topics in Medicinal Chemistry Special FBDD Issue

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This year ends with an entire issue of Current Topics in Medicinal Chemistry devoted to FBDD. Rob van Montfort and Ian Collins provide a b...