Practical Fragments

This blog is meant to allow Fragment-based Drug Design Practitioners to get together and discuss NON-CONFIDENTIAL issues regarding fragments.

Showing posts with label Kd. Show all posts

Showing posts with label Kd. Show all posts

01 December 2025

A sharp NMR trick for rapidly measuring affinities

As noted in our poll last year, ligand-detected NMR ranks among the most popular fragment-finding approaches. The various methods are able ...

21 October 2015

LO-MS...Coming of Age.

There are many ways to screen for fragments. One of the really emerging areas uses mass spec detection: WAC , native mass spec , HDX , and...

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