tag:blogger.com,1999:blog-1136153439451224584.post5334848028862030752..comments2024-03-27T06:45:59.174-07:00Comments on Practical Fragments: Ligand efficiency invalidated!Dr. Teddy Zhttp://www.blogger.com/profile/07288045760981372367noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-1136153439451224584.post-23624325350127127882017-04-05T06:14:05.230-07:002017-04-05T06:14:05.230-07:00Jesting aside, as near as I can tell this post acc...Jesting aside, as near as I can tell this post accurately summarizes Pete's <a href="http://fbdd-lit.blogspot.com/2014/09/saving-ligand-efficiency.html" rel="nofollow">criticism</a> of ligand efficiency. What I found interesting when writing it was how insensitive LE is to the definition of standard state: it actually took quite a bit of tweaking to contrive an example where Terran ligand efficiency increased while Venusian ligand efficiency decreased. In other words, the criticism is irrelevant, at least for Earthlings.Dan Erlansonhttps://www.blogger.com/profile/07927082337051189270noreply@blogger.comtag:blogger.com,1999:blog-1136153439451224584.post-52536270500159510512017-04-04T12:35:04.675-07:002017-04-04T12:35:04.675-07:00The authors did not mention, that skiing in April ...The authors did not mention, that skiing in April is wonderful on Venus. Otherwise, great research ;)Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1136153439451224584.post-5484415504099170382017-04-03T10:52:51.876-07:002017-04-03T10:52:51.876-07:00Good one!Good one!Anonymousnoreply@blogger.com