tag:blogger.com,1999:blog-1136153439451224584.post6668835677445909427..comments2024-03-27T06:45:59.174-07:00Comments on Practical Fragments: Fragments in the clinic: 2013 editionDr. Teddy Zhttp://www.blogger.com/profile/07288045760981372367noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-1136153439451224584.post-43234484946903080342014-09-27T02:08:06.787-07:002014-09-27T02:08:06.787-07:00last time i checked AZD5363 is now in phase 2. and...last time i checked AZD5363 is now in phase 2. and it isnt really an astex compound, rather it came from the CR-UK/ICR side of the collaboration. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1136153439451224584.post-58455579401219324252014-08-17T10:22:07.969-07:002014-08-17T10:22:07.969-07:00Vernalis and Servier recently announced that their...Vernalis and Servier recently announced that their BCL-2 inhibitor has entered Phase I:<br /><br />http://www.vernalis.com/media-centre/latest-releases/684-vernalis-and-servier-achieve-research-milestone-as-bcl-2-inhibitor-drug-candidate-enters-phase-iDan Erlansonhttps://www.blogger.com/profile/07927082337051189270noreply@blogger.comtag:blogger.com,1999:blog-1136153439451224584.post-79020417936847433822013-01-17T17:58:13.577-08:002013-01-17T17:58:13.577-08:00Here's the press release for AT13148:
http://...Here's the press release for AT13148:<br /><br />http://www.fiercebiotech.com/press-releases/astex-pharmaceuticals-inc-cancer-research-uk-and-cancer-research-technology?utm_medium=nl&utm_source=internalDan Erlansonhttps://www.blogger.com/profile/07927082337051189270noreply@blogger.comtag:blogger.com,1999:blog-1136153439451224584.post-78456963339910885042013-01-12T15:31:54.302-08:002013-01-12T15:31:54.302-08:00Good idea Chris - this post now has a link on the ...Good idea Chris - this post now has a link on the sidebar for easier access.<br /><br />Thanks BioDueDiligence for the tip on AT13148.<br /><br />I just came across a selective Abbott Bcl-2 inhibitor, ABT-199, in Phase 1b:<br /><br />http://www.sciencedirect.com/science/article/pii/B9780123964922000175Dan Erlansonhttps://www.blogger.com/profile/07927082337051189270noreply@blogger.comtag:blogger.com,1999:blog-1136153439451224584.post-25199786903081576672013-01-11T03:44:19.481-08:002013-01-11T03:44:19.481-08:00Might be useful to have a link to this list in the...Might be useful to have a link to this list in the sidebar?Chrishttps://www.blogger.com/profile/11553312663186781938noreply@blogger.comtag:blogger.com,1999:blog-1136153439451224584.post-33207944005281530472013-01-05T18:52:15.491-08:002013-01-05T18:52:15.491-08:00Great list - thanks for updating. Astex has one mo...Great list - thanks for updating. Astex has one more drug AT13148, an AGC Kinase inhibitor starting phase 1 trials in oncology.@BioDueDiligencehttp://www.biotechduediligence.comnoreply@blogger.com