tag:blogger.com,1999:blog-1136153439451224584.post1635135681642854632..comments2024-03-27T06:45:59.174-07:00Comments on Practical Fragments: The Rule of 1Dr. Teddy Zhttp://www.blogger.com/profile/07288045760981372367noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-1136153439451224584.post-25708946192559157622010-04-04T00:58:46.784-07:002010-04-04T00:58:46.784-07:00Eh, it's been done. Dagmar Ringe back in the n...Eh, it's been done. Dagmar Ringe back in the nineties. Not as a company though and just to identify binding hot spots, not for fragment starting points for med chem. It's called multiple solvent crystal structures and it is pretty cool but I would say that it has been replaced by computational methods. And yes I do realise that this is an April Fool's joke and I got it when I got to Lilliputian or there abouts but any good April Fool's has a core of truth.Bastardhttps://www.blogger.com/profile/04773584479244051660noreply@blogger.com